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DeCS
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Descriptor English:
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Zinc Finger E-box-Binding Homeobox 1
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Descriptor Spanish:
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Homeobox 1 de Unión a la E-Box con Dedos de Zinc
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Descriptor Portuguese:
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Homeobox 1 de Ligação a E-box em Dedo de Zinco
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Synonyms English:
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NIL 2 A Zinc Finger Protein
NIL-2-A Zinc Finger Protein
TCF8 Protein
Transcription Factor 8
Transcription Factor, Zeb1
Zeb1 Transcription Factor
Zinc Finger E box Binding Homeobox 1
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Tree Number:
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D12.776.260.400.906
D12.776.260.703.800
D12.776.930.780.945
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Definition English:
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A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56604
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Unique Identifier:
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D000071799
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Occurrence in VHL:
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Similar:
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DeCS
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